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The Anatomy of Melancholy by Robert Burton. The Anatomy of Melancholy (full title: The Anatomy of Melancholy, What it is: With all the Kinds, Causes, Symptomes, Prognostickes, and Several Cures of it. In Three Maine Partitions with their several Sections, Members, and Subsections. Philosophically, Medicinally, Historically, Opened and Cut Up) is a book by Robert Burton, first published in 1621, but republished four more times over the next seventeen years with massive alterations and expansions. On its surface, the book is presented as a medical textbook in which Burton applies his vast and varied learning, in the scholastic manner, to the subject of melancholia (which includes, although it is not limited to, what is now termed clinical depression). Although presented as a medical text, The Anatomy of Melancholy is as much a sui generis work of literature as it is a scientific or philosophical text, and Burton addresses far more than his stated subject. In fact, the Anatomy uses melancholy as the lens through which all human emotion and thought may be scrutinized, and virtually the entire contents of a 17th-century library are marshalled into service of this goal. It is encyclopedic in its range and reference.